Latissimus Dorsi Flap for Chemotherapy-induced Extensive Forearm Necrosis: Case Study

Chemotherapeutic drug extravasation represents one of the most prevalent complications encountered during chemotherapy administration in oncology patients. A severe consequence of this complication is the induction of extensive soft-tissue necrosis, for which a definitive clinical management protocol remains elusive. This study presented and analyzed a case of an older male patient who developed extensive soft-tissue necrosis in the forearm due to chemotherapeutic drug extravasation, prompting his admission to our department for treatment. The patient underwent repeated debridement procedures, followed by the application of a latissimus dorsi myocutaneous flap combined with skin grafting to cover the wound surface. A 2-month postoperative follow-up revealed satisfactory growth of both the flap and skin graft. This flap transfer technique offers a novel therapeutic approach for the management of extensive soft-tissue necrosis resulting from chemotherapeutic drug extravasation.