Related Experiment Video
Updated: Sep 17, 2025
Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Collagen crosslinking in thin corneas
Aniruddh Heroor1, Rashmi Deshmukh
1Cataract and Refractive Services, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Background:
Collagen cross linking (CXL) is the only modality that can arrest or mitigate the progression of keratoconus. However, conventional CXL using the Dresden protocol cannot be used in corneas less than 400 µm in thickness due to the risk of endothelial damage. A number of modifications have been implemented to solve this problem.
Purpose:
To highlight the parameters used in the Dresden protocol, its pitfalls in thin corneas and elucidate the modifications that allow cross-linking in thin corneas.
Synopsis:
This video serves to present the Dresden protocol, the ensuing problem in thinner corneas and elucidate the myriad of interesting alternatives currently available to tackle this difficulty.
Video Link:
https://youtu.be/wXmR_NSJTvk.
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