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Updated: Sep 17, 2025

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Oncofertility and female fertility preservation: a clinical update
1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.
Abstract:
Certain cancer and medical treatments can be harmful to fertility by depleting the egg supply. The risk to fertility is dependent on the patient's age, ovarian reserve before treatment, specific medication, or treatment and dosage. For women at risk of developing ovarian insufficiency because of gonadotoxic treatment, fertility preservation options include embryo, oocyte, and ovarian-tissue cryopreservation. Surgical procedures that can protect fertility for patients facing pelvic radiation therapy include ovarian transposition and uterine transposition. This Practice Pearl will focus on fertility preservation options for women facing medical treatment, a core component of oncofertility.
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