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Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Aptamer-based biosensors for tobramycin.

Jizhao Zhang1,2,3, Qiang Zhao1,2,3

  • 1School of Environment, Hangzhou Institute for Advanced Study, UCAS, Hangzhou 310024, China.

Analytical Methods : Advancing Methods and Applications
|June 30, 2025
PubMed
Summary
This summary is machine-generated.

Rapid detection of tobramycin is crucial due to environmental and health risks. Aptamer-based biosensors offer a promising solution for sensitive and selective tobramycin detection in various applications.

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Environmental Science

Background:

  • Widespread tobramycin use leads to environmental contamination and health concerns.
  • Accurate and swift detection methods for tobramycin are urgently needed.
  • Aptamers offer high specificity and affinity for target molecules like tobramycin.

Purpose of the Study:

  • To review the selection and characterization of DNA and RNA aptamers for tobramycin.
  • To summarize recent advancements in aptamer-based biosensors for tobramycin detection.
  • To analyze the principles, applications, advantages, and limitations of these biosensors.

Main Methods:

  • Selection of DNA and RNA aptamers against tobramycin.
  • Development and characterization of aptamer-based biosensors (electrochemical, colorimetric, fluorescence).
  • Review of existing literature on aptamer-based tobramycin detection.

Main Results:

  • Aptamers have been successfully selected for tobramycin recognition.
  • Various aptamer-based biosensors demonstrate high sensitivity and selectivity.
  • Different sensor platforms offer diverse detection capabilities and performance metrics.

Conclusions:

  • Aptamer-based biosensors are effective tools for tobramycin detection.
  • These biosensors hold significant potential for environmental monitoring and medical diagnostics.
  • Further research can optimize sensor performance and expand application scope.