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Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

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Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
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Endoscopic Transoropharyngeal Retropharyngeal Lymph Node (RPLN) Dissection for RPLN Recurrence Nasopharyngeal

You-Ping Liu1,2,3,4,5,6, Hai-Bo Wu2,3,4,5,6, Zheng-Kai Feng1

  • 1Nasopharyngeal Cancer Center, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, People's Republic of China.

Annals of Surgical Oncology
|June 30, 2025
PubMed
Summary

Endoscopic transoropharyngeal dissection effectively treats recurrent retropharyngeal lymph node (RPLN) metastasis in nasopharyngeal carcinoma (NPC) patients. This minimally invasive approach shows promising tumor control and acceptable patient outcomes.

Keywords:
EndoscopicNasopharyngeal carcinomaRetropharyngeal lymph nodeSurvivalTransoropharyngeal

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Area of Science:

  • Otolaryngology
  • Surgical Oncology
  • Head and Neck Cancer Research

Background:

  • Retropharyngeal lymph node (RPLN) dissection presents surgical challenges with no ideal approach.
  • Recurrence of RPLN in nasopharyngeal carcinoma (NPC) necessitates effective treatment strategies.

Purpose of the Study:

  • To evaluate the efficacy of endoscopic transoropharyngeal RPLN dissection for patients with recurrent NPC.
  • To assess tumor control, survival rates, and complications associated with this minimally invasive technique.

Main Methods:

  • Retrospective analysis of 25 patients with RPLN recurrence of NPC undergoing endoscopic transoropharyngeal RPLN dissection.
  • Data collected included clinical characteristics, surgical outcomes (time, blood loss), complications, and survival rates.

Main Results:

  • The procedure involved an average surgical time of 215 minutes and blood loss of 27.8 mL.
  • With a median follow-up of 20 months, 2-year survival rates were high: overall (91.5%), locoregional relapse-free (91.7%), RPLN relapse-free (100%), distant metastasis-free (90.9%), and progression-free (83.3%).
  • Only three patients experienced mild (grade 1) long-term morbidities.

Conclusions:

  • Endoscopic transoropharyngeal RPLN dissection is a minimally invasive option for managing recurrent RPLN in NPC.
  • The technique provides satisfactory tumor control and acceptable morbidity rates.
  • This approach offers a viable solution for challenging RPLN dissections in NPC recurrence.