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Updated: Sep 17, 2025

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants
Published on: December 14, 2014
Personalizing motion sickness models: estimation and statistical modeling of individual-specific parameters
Varun Kotian1, Daan M Pool2, Riender Happee1
1Faculty of Mechanical Engineering, Cognitive Robotics, Delft University of Technology, Delft, Netherlands.
Abstract:
As users transition from drivers to passengers in automated vehicles, they often take their eyes off the road to engage in non-driving activities. In driving simulators, visual motion is presented with scaled or without physical motion, leading to a mismatch between expected and perceived motion. Both conditions elicit motion sickness, calling for enhanced vehicle and simulator motion control strategies. Given the large differences in sickness susceptibility between individuals, effective countermeasures must address this at a personal level. This paper combines a group-averaged sensory conflict model with an individualized Accumulation Model (AM) to capture individual differences in motion sickness susceptibility across various conditions. The feasibility of this framework is verified using three datasets involving sickening conditions: (1) vehicle experiments with and without outside vision, (2) corresponding vehicle and driving simulator experiments, and (3) vehicle experiments with various non-driving-related tasks. All datasets involve passive motion, mirroring experience in automated vehicles. The preferred model (AM2) can fit individual motion sickness responses across conditions using only two individualized parameters (gain K 1 and time constant T 1) instead of the original five, ensuring unique parameters for each participant and generalisability across conditions. An average improvement factor of 1.7 in fitting individual motion sickness responses is achieved with the AM2 model compared to the group-averaged AM0 model. This framework demonstrates robustness by accurately modeling distinct motion and vision conditions. A Gaussian mixture model of the parameter distribution across a population is developed, which predicts motion sickness in an unseen dataset with an average RMSE of 0.47. This model reduces the need for large-scale population experiments, accelerating research and development.
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