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Updated: Sep 17, 2025
Milk Collection in the Rat Using Capillary Tubes and Estimation of Milk Fat Content by Creamatocrit
Published on: December 16, 2015
Estimating β-casomorphin-7 exposure from milk and dairy product consumption: a comprehensive assessment for the
Francesca Danesi1,2, Filippo Rossi3, Giulia Leni3
1Department of Agricultural and Food Sciences (DISTAL), University of Bologna, Cesena, Italy.
Abstract:
β-Casomorphin-7 (BCM-7), a heptapeptide derived from β-casein hydrolysis, has gained attention for its potential role in gastrointestinal discomfort and certain diseases, yet its effects remain controversial. This study aimed to provide the first reliable estimation of BCM-7 exposure for low, medium and high consumers of milk and dairy products in the European population. We developed a database on BCM-7 released after simulated digestion, combining literature review and direct analysis of milk and selected dairy products. Using European food consumption data, we estimated BCM-7 daily exposure for adults (132-2541 μg), adolescents (163-2594 μg) and children (200-2357 μg). Milk emerged as the most significant source of BCM-7 exposure across all population groups. Statistical analysis revealed differences in exposure levels between adults and children at medium consumption levels. This work provides the first comprehensive estimation of dietary BCM-7 exposure, laying the groundwork for future research on its potential health effects.
