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Microbial Biosensors01:17

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Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Bridging the Bio-Electronic Interface with Biofabrication
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Smart biosensors with self-healing materials.

Mohammad Ali Farzin1, Seyed Morteza Naghib1, Navid Rabiee2,3,4,5

  • 1Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran, Iran. naghib@iust.ac.ir.

Journal of Materials Chemistry. B
|July 1, 2025
PubMed
Summary

Self-healing materials enhance biosensor durability by automatically repairing damage, extending lifespan and reducing waste. This innovation is key for advanced applications like electronic skins and implantable devices.

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Area of Science:

  • Materials Science
  • Biotechnology
  • Sensor Technology

Background:

  • Biosensors require high durability for real-time, continuous operation, but often suffer from mechanical and functional degradation.
  • Self-healing materials offer a solution by enabling automatic recovery from physical damage, significantly extending sensor lifespan.

Purpose of the Study:

  • To review the latest innovations in self-healing biosensors.
  • To discuss the fundamental design strategies and implementation of self-healing materials in biosensing.
  • To explore future research directions and emerging applications.

Main Methods:

  • Review of recent literature on self-healing materials and biosensor technologies.
  • Categorization of self-healing biosensors by design and application (e.g., E-skins, eutectogels, textiles, implantable, electrochemical, fire, underwater).
  • Analysis of design strategies for self-healing material integration into biosensor platforms.

Main Results:

  • Self-healing materials significantly improve biosensor longevity, reduce maintenance, and minimize environmental impact.
  • Applications span electronic skins, smart textiles, soft robotics, implantable and underwater biosensors, and wireless sensor networks.
  • Integration of self-healing capabilities accelerates development of resilient Internet of Things (IoT) and human-machine interfaces.

Conclusions:

  • Self-healing materials are crucial for developing the next generation of robust and intelligent biosensors.
  • Continued research in self-healing material design and biosensor integration will unlock new possibilities.
  • These advancements promise more reliable and sustainable biosensing solutions across diverse fields.