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Chitosan-Graphene Composite for Drug Delivery in Cancer Therapy: Recent Progress and Advances
Negar Lari Lavasani1, Mohammad Hossein Roozbahani1, Seyed Morteza Naghib1
1Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology, 1684613114, Tehran, Iran.
Graphene/chitosan nanocomposites show promise for anticancer drug delivery due to their unique properties. This combination enhances drug efficacy and offers biocompatibility for cancer therapy applications.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Cancer Therapy
Background:
- Chitosan (CS) is a biodegradable, non-toxic biopolymer with antibacterial properties, ideal for therapeutic applications.
- Graphene oxide is biocompatible, cost-effective, and non-toxic, suitable for diverse applications.
- Graphene/chitosan nanocomposites offer unique physical, chemical, and electrical properties for enhanced drug delivery.
Purpose of the Study:
- To review anticancer drug delivery systems utilizing graphene/chitosan (CS) nanocomposites.
- To explore the potential of chitosan/graphene oxide composites in wound dressings and cancer therapy.
- To examine the combined benefits of chitosan and graphene for enhanced therapeutic outcomes.
Main Methods:
- Literature review of existing research on graphene/chitosan nanocomposites for drug delivery.
- Analysis of the properties of chitosan and graphene oxide relevant to biomedical applications.
- Investigation into the synergistic effects of combining chitosan and graphene.
Main Results:
- Graphene/chitosan nanocomposites demonstrate improved drug efficacy in delivery systems.
- Chitosan's inherent properties and graphene oxide's biocompatibility make them suitable for cancer treatment.
- The combination of CS and graphene is under investigation for enhanced therapeutic benefits.
Conclusions:
- Graphene/chitosan nanocomposites represent a promising platform for advanced anticancer drug delivery.
- The synergistic combination of chitosan and graphene offers significant potential for cancer therapy and wound healing.
- Further research into these nanocomposites could lead to more effective cancer treatment strategies.
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