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Hepatic necrosis with doxapram hydrochloride.
Postgraduate Medical Journal
|September 1, 1985
Summary
This study details the first reported case of acute hepatic necrosis, a severe liver condition, potentially caused by the respiratory stimulant doxapram hydrochloride (Dopram). Further investigation into this adverse drug reaction is warranted.
Area of Science:
- Hepatology
- Pharmacology
- Toxicology
Background:
- Doxapram hydrochloride (Dopram) is a respiratory stimulant used in clinical settings.
- Adverse drug reactions can manifest in various organ systems.
- The liver is a primary site for drug metabolism and potential toxicity.