Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Usefulness of Cytokeratin Fragment Antigen 21-1 Estimation in Fine-Needle Aspiration Washout Specimens in Diagnosis of Axillary Breast Cancer Metastasis.

Journal of cytology·2026

Same author

Pelvic desmoid fibromatosis: a diagnostic and therapeutic challenge.

BMJ case reports·2026

Same author

Primary Chondrosarcoma of the Breast: A Diagnostic and Histopathologic Challenge.

Indian journal of surgical oncology·2026

Same author

Target-based Antidiabetic Indole Derivatives and Insights into Structure-activity Relationships: A Mechanistic Update 2020-2025.

Current drug targets·2026

Same author

Association of Vasomotor Symptoms and Cardiac Autonomic Functions in Perimenopausal Women.

Journal of mid-life health·2026

Same author

Giant primary splenic hydatid cyst: diagnostic and therapeutic challenges.

BMJ case reports·2026

Same journal

Intraoperative endoscopic detection of multiple ciliary body cysts not detected preoperatively.

BMJ case reports·2026

Same journal

Can focal nodular hyperplasia transform into hepatocellular carcinoma? A 20-year journey from benign to malignant.

BMJ case reports·2026

Same journal

Isolated jejunal tuberculosis presenting as chronic intestinal obstruction.

BMJ case reports·2026

Same journal

Revision of diagnosis in a child with type 1 diabetes mellitus due to appropriate genetic testing - Wolfram Syndrome.

BMJ case reports·2026

Same journal

Bilateral corneal perforation following post-PRK fungal keratitis managed with tenons patch graft.

BMJ case reports·2026

Same journal

Early onset cerebral oedema in adult diabetic ketoacidosis with complete resolution.

BMJ case reports·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Sep 17, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

Primary renal leiomyosarcoma.

Samikshya Thapa¹, Akanksha Gupta¹, Vikas Kumar Panwar²

¹Pathology and Laboratory Medicine, All India Institute of Medical Sciences - Rishikesh, Rishikesh, Uttarakhand, India.

BMJ Case Reports

|July 1, 2025

Summary

This summary is machine-generated.

Kidney leiomyosarcoma is a rare, aggressive cancer originating from smooth muscle cells. Surgical removal offers the best treatment, but long-term monitoring is crucial due to recurrence risk.

Keywords:

Cancer Pathology Renal system Urological cancer

More Related Videos

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy

Published on: April 29, 2014

Related Experiment Videos

Last Updated: Sep 17, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy

Published on: April 29, 2014

Area of Science:

Oncology
Urology
Pathology

Background:

Kidney leiomyosarcoma is an exceptionally rare and aggressive malignancy arising from smooth muscle cells within the renal parenchyma or pelvis.
It accounts for less than 1% of all renal tumors and presents with nonspecific clinical features, complicating diagnosis.
This cancer predominantly affects adults, with some reported cases showing a slight female predilection.

Purpose of the Study:

To present a case of kidney leiomyosarcoma in a male patient.
To highlight the diagnostic challenges and treatment strategies for this rare renal tumor.

Main Methods:

Case report presentation.
Review of clinical presentation, diagnostic workup, and treatment of kidney leiomyosarcoma.

Main Results:

A male patient in his early 60s presented with a 2-month history of abdominal pain, diagnosed with kidney leiomyosarcoma.
Surgical resection with clear margins was the primary treatment modality.
Adjuvant therapies like chemotherapy and radiation showed limited efficacy.

Conclusions:

Kidney leiomyosarcoma is a challenging diagnosis due to its rarity and nonspecific symptoms.
Surgical resection is the mainstay of treatment, but a significant risk of recurrence necessitates long-term patient surveillance.