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Precise surface patches on active particles of arbitrary shape through microstenciling.
Kendra M Kreienbrink1, Zoe A Cruse2, Alisha Kumari3
1Materials Science and Engineering Program, University of Colorado Boulder, Boulder, CO, 80303, USA.
Nature Communications
|July 2, 2025
Summary
Researchers developed a novel microstenciling technique to fabricate precise active particles. This method enables the creation of complex micro-robots for applications in microrobotics and biomedicine.
Area of Science:
- Materials Science
- Micro- and Nanotechnology
- Physics
Background:
- Active particles harness environmental energy for programmable motion and collective behaviors.
- Particle shape and surface modifications advance applications in microrobotics and biomedicine.
- Conventional fabrication methods limit the precise creation of arbitrary active particles.
Purpose of the Study:
- To introduce a high-resolution microstenciling fabrication technique for arbitrary active particles.
- To overcome limitations in creating active particles with precise shapes and surface compositions.
Main Methods:
- Combines two-photon lithography with sacrificial stencil masking.
- Enables deposition of arbitrary metallic patches onto particles of any shape.
- Achieves a resolution limit as low as 0.2 micrometers.
Main Results:
- Demonstrated three types of active particles with nonconventional dynamics.
- Created electrokinetic active spheres with tunable 3D motions.
- Fabricated catalytic microdiscs exhibiting chiral axial spinning and steric magnetic particles forming self-limiting microrobots.
Conclusions:
- The high-resolution microstenciling technique is a versatile strategy for fabricating well-defined active particles.
- This method facilitates the creation of advanced active particles and microrobots.
- Enables diverse practical applications in microrobotics, biomedicine, and beyond.

