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Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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INTERVENTIONAL TRAPS IN ECTATIC CORONARY ARTERIES: A CASE REPORT.

Krešimir Gabaldo1,2, Marijana Knežević Praveček1,2, Domagoj Vučić1,2,3

  • 1Department of Internal Medicine, Dr. Josip Benčević General Hospital, Slavonski Brod, Croatia.

Acta Clinica Croatica
|July 2, 2025
PubMed
Summary
This summary is machine-generated.

Coronary artery aneurysms increase percutaneous intervention risks, causing the no-reflow phenomenon. This case study shows successful management and recovery despite initial complications in a patient with right coronary artery aneurysm.

Keywords:
acute coronary syndromeaneurysmsno-reflowthromboaspiration

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Medicine

Background:

  • Coronary artery ectasia (CAE) or aneurysms involve arterial dilatation (>1.5x normal diameter), leading to disturbed blood flow and thrombosis.
  • Percutaneous coronary interventions (PCI) in CAE carry high risks, notably the no-reflow phenomenon, common in acute coronary syndromes like ST-elevation myocardial infarction (STEMI).

Observation:

  • This case details the no-reflow phenomenon in a stable patient undergoing PCI for significant stenosis in an aneurysmally altered right coronary artery.
  • Despite prompt stenting, optimized therapy, and thromboaspiration, TIMI 3 flow was not achieved, leading to periprocedural STEMI.

Findings:

  • The patient was successfully stabilized post-STEMI, exhibiting unexpectedly good recovery of myocardial function.
  • Follow-up angiography at 6 weeks confirmed proper stent patency and restored normal TIMI 3 flow.

Implications:

  • This case highlights the challenges of PCI in coronary aneurysms and the potential for successful outcomes despite initial no-reflow complications.
  • Effective management strategies can lead to favorable long-term results, even after periprocedural myocardial infarction.