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Mastoid obliteration with bone dust mixed with concentrated growth factor
Sabri Baki Eren1, Alper Yenigun1, Erol Senturk1
1Bezmialem Vakif University, Faculty of Medicine, Department of Otorhinolaryngology, Fatih, Istanbul, Turkey.
American Journal of Otolaryngology
|July 2, 2025
Summary
Mastoid obliteration using a mixture of concentrated growth factors (CGF) and bone dust is an effective surgical technique. This method successfully creates a natural external ear canal, improving outcomes for chronic ear infections and cholesteatoma treatment.
Area of Science:
- Otolaryngology
- Surgical Innovation
- Regenerative Medicine
Background:
- Mastoid obliteration is a key surgical step for chronic ear conditions.
- This technique involves filling the mastoid cavity with graft materials after air cell removal.
Purpose of the Study:
- To evaluate the benefits of mastoid obliteration using a combination of concentrated growth factors (CGF) and bone dust.
- To assess the efficacy of this novel technique in reconstructive ear surgery.
Main Methods:
- Bone dust was harvested from the healthy mastoid cortex.
- The bone dust was combined with CGF to create a gel-like substance.
- This mixture was used to obliterate the mastoid cavity and epitympanum.
Main Results:
- The study included fifteen patients who underwent canal wall down mastoidectomy for cholesteatoma.
- Successful obliteration was achieved in all cases.
- The procedure resulted in the desired external ear canal and hearing outcomes.
Conclusions:
- Mastoid obliteration with CGF and bone dust is an effective surgical approach.
- This technique facilitates the creation of a natural and healthy external ear canal.
- It offers a viable solution for mastoid obliteration in chronic ear infections and cholesteatoma management.

