Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Function Tests

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...

Respiratory Volumes and Capacities

Respiratory Volumes and Capacities

The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

Lung Capacity

Lung Capacity

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.

Respiratory Capacities

Respiratory Capacities

Respiratory capacities are crucial indicators of lung function, representing the maximum amount of air an individual's respiratory system can handle during various breathing phases.
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dual-Function Halide Exchange Strategy for Simultaneous Sn<sup>4+</sup> Elimination and Stability Enhancement in Pb-Sn Mixed Perovskite Solar Cells.

ACS nano·2026

Same author

The relationship between home environment and infant neuropsychological outcomes: Comparison between preterm and full-term infants.

Early human development·2026

Same author

Impact of Staged Rehabilitation Training on Urinary Incontinence Recovery After Radical Prostatectomy: A Retrospective Analysis.

American journal of men's health·2026

Same author

Author Correction: Boosting mechanical durability under high humidity by bioinspired multisite polymer for high-efficiency flexible perovskite solar cells.

Nature communications·2026

Same author

Development and internal validation of a nomogram for identifying intrinsic capacity impairment among community-dwelling older adults in China: a cross-sectional study.

BMC geriatrics·2026

Same author

Treatment efficacy of butylphthalide and sodium chloride injection combined with argatroban on neurological function and hemorheological parameters in ischemic stroke.

American journal of translational research·2026

Search research articles

Related Experiment Video

Updated: Sep 17, 2025

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

Reference equations for pulmonary function testing in healthy Chinese children aged 4-18 years.

Jinhong Wu¹, Hao Zhang², Yufen Wu¹

¹Department of Internal Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 400127, China.

Respiratory Research

|July 3, 2025

Summary

This summary is machine-generated.

New spirometry reference equations were developed for healthy Chinese children, offering improved accuracy for diagnosing respiratory conditions. These equations account for contemporary growth and regional diversity, outperforming existing global and Chinese models.

Keywords:

Chinese children Pulmonary function test Reference equations Spirometry

More Related Videos

Conducting Respiratory Oscillometry in an Outpatient Setting

Conducting Respiratory Oscillometry in an Outpatient Setting

Published on: April 8, 2022

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

Related Experiment Videos

Last Updated: Sep 17, 2025

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

Conducting Respiratory Oscillometry in an Outpatient Setting

Conducting Respiratory Oscillometry in an Outpatient Setting

Published on: April 8, 2022

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

Area of Science:

Pulmonary Medicine
Pediatric Respiratory Health
Biostatistics

Background:

Accurate spirometry reference equations are crucial for diagnosing and managing pediatric respiratory diseases.
Existing global equations (e.g., GLI) have limited data from Asian populations.
There is a need for spirometric reference equations specific to healthy Chinese children.

Purpose of the Study:

To develop and validate new spirometric reference equations for healthy Chinese children aged 4-18 years.
To compare the performance of these new equations against existing Caucasian and Chinese pediatric reference equations.
To provide accurate tools for assessing lung function in the Chinese pediatric population.

Main Methods:

A cross-sectional study of 8929 healthy Chinese Han children (aged 4-18) was conducted across 24 regions in China.
Spirometry, physical measurements (height, weight), and demographic data were collected.
Multiple linear regression models incorporating age, height, and weight were used to develop new prediction equations.

Main Results:

Age, weight, and height were significant predictors of lung function (p < 0.001).
Newly developed sex-specific equations showed high accuracy in internal validation (mean z-scores: -0.004 to -0.069).
Existing Zapletal and GLI equations demonstrated over/underestimations of lung function parameters compared to the new Chinese equations.

Conclusions:

New spirometry reference equations tailored for healthy Chinese children have been developed.
These equations reflect current growth patterns and regional variations within China.
The new equations offer a valuable, accurate clinical tool for pediatric respiratory assessments in China.