Related Experiment Video
Updated: Sep 17, 2025

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Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
Published on: April 14, 2023
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Living Donor Uterus Transplantation
Masato Tamate1, Giuliano Testa, Laura Divine
1Department of Transplant Surgery, Annette C. and Harold C. Simmons Transplant Institute, and the Division of Obstetrics and Gynecology, Baylor University Medical Center, Dallas, Texas.
Obstetrics and Gynecology
|July 3, 2025
Summary
Uterus transplantation offers a path to pregnancy for women with uterine factor infertility. This procedure involves complex surgical and medical steps, leading to successful births of healthy children.
Area of Science:
- Reproductive medicine
- Transplant surgery
Background:
- Uterus transplantation is a temporary procedure for women with absolute uterine factor infertility.
- It aims to enable normal gestation and delivery.
- The process involves multiple surgical and medical interventions.
Purpose of the Study:
- To demonstrate the surgical steps of a living donor uterus transplant.
- To highlight the key phases of the uterus transplant journey.
Main Methods:
- Surgical steps include donor hysterectomy, graft transplantation, cesarean delivery, and graft hysterectomy.
- Medical management involves immunosuppression, in vitro fertilization, and pregnancy monitoring.
- The video showcases a living donor procedure from hysterectomy to recipient transplant.
Main Results:
- 36 uterus transplantations performed between September 2016 and January 2025.
- 26 children have been born following uterus transplantation.
- The study highlights the successful outcomes of uterus transplantation.
Conclusions:
- Uterus transplantation is a viable option for achieving pregnancy.
- The procedure is associated with the birth of healthy children.
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