Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Double Resonance Techniques: Overview01:12

Double Resonance Techniques: Overview

303
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
303

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

4D-aware stereo matching via implicit spectral reconstruction with multi-modal training and RGB-only deployment.

Optics express·2026
Same author

Engineered immune cells and extracellular vesicles target tumour microenvironment barriers in solid tumour immunotherapy.

Discover oncology·2026
Same author

Correction to "<i>Treponema pallidum</i> Flagellin FlaB3 Activates Inflammation and Inhibits Autophagy in HMC3 Cells via the TLR4 Pathway".

ACS infectious diseases·2026
Same author

Dual-Functional Metal Interlayer Enables High-Quality GaN Epitaxy and Low-Damage Transfer Towards Flexible Optoelectronics.

Small methods·2026
Same author

Voice-controlled super-resolution ultrasound imaging and reporting powered by multimodal large language models.

NPJ digital medicine·2026
Same author

Research Advances in MicroRNA-Mediated Regulation of Bamboo Organ Development.

Plants (Basel, Switzerland)·2026
Same journal

Large-scale discovery and annotation of substructure patterns in mass spectrometry profiles.

Nature communications·2026
Same journal

Salmonella SopB suppresses post-transcriptionally regulated cytokine release to reduce early tissue inflammation and delay disease progression.

Nature communications·2026
Same journal

A human-specific microRNA controls the timing of excitatory synaptogenesis.

Nature communications·2026
Same journal

An HMA-like integrated domain in the wheat tandem kinase WTK4 recognises an RNase-like pathogen effector.

Nature communications·2026
Same journal

Learning regularities in noise engages both neural predictive activity and representational changes.

Nature communications·2026
Same journal

The H3K4 methyltransferase KMT2D is an essential cofactor for GATA1 at erythroid gene enhancers.

Nature communications·2026
See all related articles

Related Experiment Video

Updated: Sep 17, 2025

Design and Characterization Methodology for Efficient Wide Range Tunable MEMS Filters
15:25

Design and Characterization Methodology for Efficient Wide Range Tunable MEMS Filters

Published on: February 4, 2018

6.2K

Ultrasensitive imaging-based sensor unlocked by differential guided-mode resonance.

Zhenchao Liu1,2,3, Houxin Fan1, Tingbiao Guo4

  • 1Centre for Optical and Electromagnetic Research, Enze-ZJU Joint Lab for MedEngInfo Collaborative Innovation, College of Optical Science and Engineering, Zhejiang University (ZJU), Hangzhou, 310058, People's Republic of China.

Nature Communications
|July 3, 2025
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel imaging sensor using differential guided-mode resonance. This breakthrough significantly boosts sensitivity and dynamic range for applications in medical diagnosis and environmental monitoring.

More Related Videos

Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors
08:32

Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors

Published on: January 29, 2013

13.4K
Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

9.5K

Related Experiment Videos

Last Updated: Sep 17, 2025

Design and Characterization Methodology for Efficient Wide Range Tunable MEMS Filters
15:25

Design and Characterization Methodology for Efficient Wide Range Tunable MEMS Filters

Published on: February 4, 2018

6.2K
Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors
08:32

Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors

Published on: January 29, 2013

13.4K
Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

9.5K

Area of Science:

  • Optoelectronics
  • Nanotechnology
  • Sensor Technology

Background:

  • Imaging-based sensors translate analyte properties into visual signals but often struggle with sensitivity limitations.
  • The trade-off between sensitivity and dynamic range has historically constrained the performance of these sensors.

Purpose of the Study:

  • To introduce a new sensing concept that enhances sensitivity and dynamic range in imaging sensors.
  • To overcome the inherent limitations of current imaging-based sensor technologies.

Main Methods:

  • Utilizing differential guided-mode resonance (GMR) with precise thickness modulation at the tens-of-nanometers scale.
  • Employing GMR principles to amplify sensor response to changes in physicochemical parameters.

Main Results:

  • Achieved record-breaking sensitivity up to a million pixels per refractive index unit (RIU), nearly 1000 times greater than existing methods.
  • Demonstrated a large dynamic range that can be tuned by adjusting the incident angle.
  • Reached a Figure of Merit (FOM) of 10^4 RIU^-1 with a moderate Q factor of approximately 100.

Conclusions:

  • The developed method significantly enhances the sensitivity and dynamic range of imaging-based sensors.
  • This technology enables practical applications in medical diagnosis, biochemical analysis, and environmental monitoring through a portable device.
  • The approach effectively alleviates the sensitivity-dynamic range tradeoff, unlocking new possibilities for high-performance sensing.