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Updated: Sep 17, 2025

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis
Published on: November 28, 2015
Scientometric analysis of lipid metabolism in macrophage polarization: 2013-2023
Chenxiao Ye1, Xiaosong Ru1, Yong Guo2
1The First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Introduction:
Macrophage polarization plays a crucial role in the development of various diseases. Simultaneously, macrophage polarization is intimately related to lipid metabolism. To assess the emerging trend of lipid metabolism during macrophage polarization, the present study was carried out.
Methods:
First, 472 publications that explored lipid metabolism during macrophage polarization were gathered using the Web of Science Core Collection database (WoSCC). The emerging trends were then described using CiteSpace.
Results:
Between 2013 and 2023, 46 countries/regions involving 268 institutions carried out studies in this field. The largest number of publications was found in China. Additionally, the most recent burst keywords included "immunometabolism", "foam cell formation", and "pathway", which represented the current frontiers of research.
Discussion:
The detailed analysis of publications pertaining to lipid metabolism during macrophage polarization reveals the current research status and identifies its hotspots.
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