Related Experiment Video
Updated: Sep 17, 2025

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
[Oral manifestations of chikungunya virus. a cross-sectional study]
María Del Carmen González Galván1, José Gamarra Insfrán1, Carlos González Casamada2
1Facultad de Odontología, Cátedra de Patología Bucal, Universidad Nacional de Asunción. Asunción, Paraguay. maricarmenggalvan@gmail.com, josemgamarra31@gmail.com Universidad Nacional de Asunción Facultad de Odontología, Cátedra de Patología Bucal Universidad Nacional de Asunción Asunción Paraguay maricarmenggalvan@gmail.com josemgamarra31@gmail.com.
Introduction:
chikungunya virus was isolated in humans for the first time in 1952 after an epidemic in Tanzania, during 2023 the largest chikungunya epidemic occurred in Paraguay.
Objective:
to determine the most frequent oral manifestations self-reported by chikungunya-infected patients in a Paraguayan population group. Materials and methods: a cross-sectional observational study was carried out during September and October 2024, with research subjects who suffered from chikungunya. The instrument had two sections: the first covered the study information and sociodemographic data. The second section indicated the presence of any oral manifestation during the course of the disease, the options were catalogued in a dichotomous manner ("yes" or "no"), the subjects who indicated the presence of any oral manifestation also indicated its intensity ("mild", "moderate" or "severe").
Results:
131 subjects participated; female sex predominated and the average age was 35 years. The three most frequent oral manifestations were gum pain (43.5%), burning sensation in the mouth (41.9%) and the presence of ulcers (31.2%). Oral ulcers were considered the most severe manifestation.
Conclusion:
the most frequently reported oral manifestations were gum pain, burning sensation and the presence of oral ulcers. In terms of intensity, the most severe oral manifestations were the presence of ulcers, difficulty in chewing and/or swallowing and loss of taste.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Myocarditis II: Clinical Features and Diagnostic Tests

