Related Experiment Video
Updated: Sep 8, 2025
08:51
Monitoring Protein Adsorption with Solid-state Nanopores
Published on: December 2, 2011
13.7K
Solid-state nanopore detection of metal ions via a DNAzyme-Catalytic Hairpin Assembly reaction
Yesheng Wang1,2,3, Lan Shao1,3, Chunmiao Yu1,2,3
1Department of Gastric Surgery, Cancer Hospital of Dalian University of Technology, Shenyang, Liaoning 110042, P. R. China. jinbozhu@dlut.edu.cn.
Chemical Communications (Cambridge, England)
|July 4, 2025
Abstract:
Based on the indirect transduction strategy (ITS), we utilize a DNAzyme-CHA reaction to transduce lead(II), which cannot be directly detected by a glass nanopore, into controllable CHA products. This enables the accurate recognition of lead(II). The signal amplification method significantly enhances the resolution of glass nanopores and is expected to broaden their application scope.
