Related Experiment Video
Updated: Sep 16, 2025

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
Development and validation of a nomogram for predicting the risk of cognitive impairment among chronic obstructive
Ying Fan1, Chao Zhang2, Zhixin Fan2
1School of Nursing, Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, China.
Background:
Cognitive impairment has been proven to have a significant impact on the overall quality of life among chronic obstructive pulmonary disease (COPD). Using a reliable and convenient method to identify the high-risk population of cognitive impairment may help to improve the prognosis of COPD patients. The aim of this study is to develop a nomogram for predicting cognitive impairment for COPD patients.
Methods:
The convenience sampling method was employed to select COPD patients for investigation. The dataset was randomly partitioned into a development subset and a validation subset. Univariate and multiple logistic regression analyses were performed on the development dataset to ascertain risk factors for cognitive impairment and to establish a nomogram to forecast the likelihood of cognitive dysfunction in COPD patients. This model was evaluated thorough discrimination, calibration, and decision curve.
Results:
Age, education level, regular exercise habits, participation in intellectual activities, FEV1/FVC, and serum albumin were significant contributing factors to cognitive impairment risk. A nomogram model for predicting cognitive impairment in COPD patients was developed based on these factors. The designed model demonstrates excellent predictive performance.
Conclusion:
The designed model can identify patients at high risk of cognitive impairment, providing empirical evidence for precise treatment and management of cognitive impairment in COPD patients.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Chronic Obstructive Pulmonary Disease-V: Nursing Management
Assessment

