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A rare B cell clonotype imprinted by ancestral SARS-CoV-2 develops cross-sarbecovirus neutralization in immune

Xixian Chen1, Ling Li2, Ruiping Du1

  • 1Laboratory of Immunoengineering, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China; University of Science and Technology of China, Hefei 230026, China.

Cell Reports
|July 5, 2025
PubMed

Keywords:
CP: ImmunologyIGHV3-53/3-66IGHV3-74SARS-CoV-2cross-sarbecovirus neutralizationepitope mappingimmune imprintingpan-SARS-CoV-2 neutralizationrepeated Omicron infection

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