A new optical fiber sensor based on the CDs@UiO66 complex fluorescence probe for nitric oxide detection

Area of Science:

• Materials Science
• Chemical Sensing
• Biomedical Engineering

Background:

• Nitric oxide (NO) plays crucial roles in biological systems.
• Accurate NO detection is vital for chemical and biomedical applications.

Purpose of the Study:

• To develop a novel optical fiber sensor for sensitive nitric oxide (NO) detection.
• To utilize a carbon quantum dots (CDs)@UiO66 complex as a fluorescence probe.

Main Methods:

• Fabrication of a NO-sensitive film using CDs@UiO66 encapsulated in cellulose acetate (CA).
• Coating the film onto an optical fiber end-face via dip-coating.
• Characterization using XRD, SEM, TEM, FTIR, fluorescence spectroscopy, and contact angle tests.

Main Results:

• The optical fiber sensor demonstrated a sensitive fluorescence intensity response to NO.
• A good linear dependence was observed for NO detection across micromolar and nanomolar levels.
• The sensor achieved a low limit of detection for NO, as low as 5 nM.

Conclusions:

• The developed optical fiber sensor offers a simple, cost-effective, and selective method for NO detection.
• This sensor shows potential for various NO detection applications.