Sarcoidosis on 18 F-FDG PET/CT : Typical and Atypical Imaging Patterns

Area of Science:

• Nuclear Medicine
• Radiology
• Pathology

Background:

• Sarcoidosis is a multisystem granulomatous inflammatory disease.
• It commonly affects the lungs and lymph nodes but can involve any organ.
• Clinical presentations and imaging findings are diverse.

Purpose of the Study:

• To present a pictorial review of 18F-FDG PET/CT findings in sarcoidosis.
• To illustrate both typical and atypical imaging patterns.
• To correlate findings with histopathologically confirmed cases.

Main Methods:

• Retrospective review of 18F-FDG PET/CT scans.
• Inclusion of patients with histopathologically confirmed sarcoidosis.
• Analysis of imaging findings across various clinical presentations.

Main Results:

• Demonstration of characteristic 18F-FDG uptake patterns in sarcoidosis.
• Illustration of unusual or atypical presentations on PET/CT.
• Correlation of imaging findings with organ involvement.

Conclusions:

• 18F-FDG PET/CT is valuable for diagnosing sarcoidosis.
• The modality can reveal both typical and atypical disease manifestations.
• Pictorial review aids in recognizing diverse sarcoidosis imaging patterns.