Related Experiment Video
Updated: Sep 16, 2025

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates
Published on: May 30, 2025
Modelling the potential impacts of limiting vaping product sales to pharmacies
Driss Ait Ouakrim1, Tim Wilson2, Samantha Howe2
1School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia drissao@unimelb.edu.au.
Background:
Vaping rates are increasing globally. Restricting vaping products' access may result in net population health loss if youths who vape switch to smoking, or net gain if it promotes cessation among people who smoke. We used simulation modelling to assess how two vaping restriction policies-over-the-counter (OTC) pharmacy access or prescription-only access via general practitioners-might impact vaping and smoking rates in Aotearoa New Zealand (A/NZ).
Methods:
We adapted an established Markov model of smoking and vaping, linked to a proportional multistate lifetable, to simulate the A/NZ population from 2023 to 2044. Three business-as-usual (BAU) scenarios ('low', 'medium' and 'high' vaping) were informed by youth vaping trends. Intervention impacts were derived from prior research and expert elicitation.
Results:
Compared with the medium BAU scenario with 50% vaping among 18-24-year olds by 2044, restricting to OTC pharmacy access reduced vaping prevalence by 6% and increased health-adjusted life years (HALYs). Only under the 'high' BAU scenario (60% vaping) did interventions marginally increase smoking (2% for OTC). Both interventions averted premature deaths and produced HALY gains.
Interpretation:
Our model suggests modest reductions in vaping prevalence and net health gains from the OTC pharmacy policy, with minor benefits from a prescription-only approach. These findings underscore the importance of balancing the potential smoking cessation benefits of vaping with the need to curb youth uptake. Future research is required to better understand how vaping restriction policies could impact vaping and smoking dynamics in A/NZ, in particular, considering how illicit supply may impact policy effectiveness.
More Related Videos
10:44Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
08:39Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Related Concept Videos
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Drug Regulation
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Model Approaches for Pharmacokinetic Data: Compartment Models
Two primary types of compartment models are recognized: mammillary and catenary. The more...
Pharmacokinetic Models: Overview
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal...
Drug Control Governance: Regulatory Bodies and Their Impact