Fluorinated Anionic Metal-Organic Frameworks for Dual-Mode Electrochemical/Photoelectrochemical Dopamine Detection

Area of Science:

• Materials Science
• Analytical Chemistry
• Nanotechnology

Background:

• Fluorinated anionic metal-organic frameworks (MOFs) offer tunable structures and electronic properties for sensing.
• Dopamine (DA) detection is crucial in biological and medical diagnostics.
• Developing sensitive and selective sensors for DA remains a significant challenge.

Purpose of the Study:

• To synthesize and characterize a novel fluorinated anionic MOF, YNU-101.
• To develop YNU-101 as a dual-mode electrochemical (EC) and photoelectrochemical (PEC) sensor for dopamine (DA).
• To investigate the sensing mechanisms and practical applicability of the YNU-101 sensor.

Main Methods:

• One-step solvothermal synthesis of YNU-101.
• Fabrication of dual-mode EC and PEC sensors using YNU-101.
• Electrochemical and photoelectrochemical measurements for DA detection.
• Density functional theory (DFT) calculations for mechanism elucidation.

Main Results:

• YNU-101 was successfully synthesized.
• The EC sensor achieved a low detection limit of 17.6 nM for DA.
• The PEC sensor demonstrated a wide detection range of 0.5-700 μM for DA.
• High selectivity and practical applicability in bovine serum samples were confirmed.

Conclusions:

• YNU-101 serves as an effective dual-mode sensor for DA detection.
• The study enhances understanding of fluorinated anionic MOFs in EC and PEC sensing.
• This work provides a strategy for developing advanced dual-mode sensing devices.