Activity of erythrocyte alanine aminotransferase in the Polish population

Alanine aminotransferase activities were tested in erythrocytes of Polish population sample of 213 adults (105 women and 108 men) and 95 children (aging 6 months to 4 years). In the tests a modified method of Wróblewski and Cabaud was used. A significant scatter of enzyme activities was noted, which ranged in adults between 0.76 and 36.86 mU/ml. In all studied groups, GPT 1 type individuals showed the highest and GPT 2 type donors the lowest activity of the enzyme. Mean activity of GPT 1 type adults was 19.27 mU/ml, in GPT 2-1 adults 13.6 mU/ml and in GPT 2 adults 8.87 mU/ml. GPT 2 type activity corresponds to approximately 46% and GPT 2-1 type activity to, approximately, 71% activity of GPT 1 type. Independently of GPT type, activity of the enzyme was lower in women in whom it amounted to 71-83% activity detected in men. In children, alanine aminotransferase activity was higher than in adults about 15-29%.