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Updated: Sep 8, 2025

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
A Case Report of Necrolytic Migratory Erythema Associated with Glucagonoma
Di Xia1, Zhouliang Liu1, Jiamin Li1
1Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, People's Republic of China.
Abstract:
Necrolytic migratory erythema(NME) is a rare dermatitis usually associated with pancreatic neuroendocrine tumor as a manifestation of glucogonoma syndrome. Over the past five years, NME has been scarcely reported in the literature, with only 8 cases globally. The age range of affected individuals spans from 28 to 62 years, with a mean onset age of 49.4 years. This report presents a 41-year-old male diagnosed with NME secondary to glucagonoma, highlighting the critical need for heightened clinical vigilance in younger NME patients. And NME can mimic other dermatological conditions, leading to potential misdiagnosis and late tumor identification. This case highlights the typical clinical features, aiming to enhance the diagnostic efficiency and accuracy for NME.
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