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Benign convulsions with mild gastroenteritis in children: An emerging acute symptomatic seizures

Duan Wang1,2,3,4,5, Lijuan Peng1,2,3,4,5, Tingsong Li1,2,3,4,5

  • 1Department of Rehabilitation Children's Hospital of Chongqing Medical University (CHCMU) Chongqing China.

Pediatric Discovery
|July 8, 2025
PubMed

Insights

Benign convulsions with mild gastroenteritis (CwG) are afebrile seizures in infants and toddlers. This review suggests CwG fits criteria for acute symptomatic seizures, not epilepsy, aiding pediatrician recognition.

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Gastroenterology

Background:

  • Benign convulsions with mild gastroenteritis (CwG) are afebrile seizures occurring during mild gastroenteritis in infants and toddlers.
  • CwG has not been formally classified by the International League against Epilepsy (ILAE) as epilepsy syndrome or acute symptomatic seizures (ASS).

Purpose of the Study:

  • To provide a comprehensive overview of CwG.
  • To aid pediatricians and general practitioners in recognizing CwG.
  • To reduce unnecessary evaluations and treatments for CwG.

Main Methods:

  • Literature review and synthesis of existing data on CwG.
  • Analysis of CwG's characteristics in relation to ASS criteria.
  • Discussion of CwG's pathogenesis, clinical presentation, and outcomes.

Main Results:

  • Accumulating evidence suggests CwG meets the criteria for ASS.
  • CwG is distinct from epilepsy, although rare cases may develop epilepsy over time.
  • Recognition of CwG can prevent over-investigation and overtreatment.

Conclusions:

  • CwG aligns with the definition of acute symptomatic seizures (ASS).
  • Distinguishing CwG from epilepsy is crucial for appropriate management.
  • Improved recognition of CwG by clinicians is needed.

Keywords:
acute symptomatic seizureschildrenconvulsionsgastroenteritisinfantself‐limited infantile epilepsy

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