Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Children's soap pH analysis and its meaning in children's skin cleansing.

Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo·2025
Same author

Prevalence and factors associated with sensitivity to methylisothiazolinone in individuals with suspected allergic contact dermatitis: A cross-sectional study.

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)·2025
Same author

Graft-versus-host disease and other cutaneous manifestations in pediatric patients transplanted for Fanconi anemia.

Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo·2023
Same author

Allergic contact cheilitis caused by propolis: case report.

Einstein (Sao Paulo, Brazil)·2022
Same author

Educational intervention and atopic dermatitis: impact on quality of life and treatment.

Asia Pacific allergy·2021
Same author

Colorimetric analysis of images in the follow-up of infantile hemangiomas.

Pediatric dermatology·2020

Related Experiment Video

Updated: Jun 23, 2026

Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model
10:13

Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model

Published on: August 23, 2015

38.4K

New cosmetics patch test series: A proposal.

Paulo Eduardo Silva Belluco1, Marjorie Uber2, Franciane de Paula da Silva3

  • 1Escola Superior de Ciências da Saúde - ESCS - Brasília/DF - Brasil. belluco@outlook.com.

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|July 8, 2025
PubMed
Summary

This study proposes an updated cosmetic patch test series to accurately identify common cosmetic allergens causing contact dermatitis. The revised 20-element series aims to improve diagnosis and patient care for facial allergic reactions.

Keywords:
AllergensContact dermatitisCosmetic contact dermatitisFragrancesPatch test

More Related Videos

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
06:31

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response

Published on: October 3, 2019

8.8K
Author Spotlight: Enhancing Skin Model Diversity with Cost-Effective 3D Cellular Models
08:32

Author Spotlight: Enhancing Skin Model Diversity with Cost-Effective 3D Cellular Models

Published on: October 20, 2023

3.0K

Related Experiment Videos

Last Updated: Jun 23, 2026

Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model
10:13

Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model

Published on: August 23, 2015

38.4K
Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
06:31

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response

Published on: October 3, 2019

8.8K
Author Spotlight: Enhancing Skin Model Diversity with Cost-Effective 3D Cellular Models
08:32

Author Spotlight: Enhancing Skin Model Diversity with Cost-Effective 3D Cellular Models

Published on: October 20, 2023

3.0K

Area of Science:

  • Dermatology
  • Allergology
  • Cosmetic Science

Background:

  • Cosmetic contact dermatitis is a prevalent condition, frequently affecting the face.
  • Patch testing is crucial for diagnosing cosmetic allergies, necessitating updated allergen series.
  • Current series require revision to include emerging allergens and exclude outdated ones.

Purpose of the Study:

  • To propose a reformulated cosmetic patch test series.
  • To identify relevant allergens in commercially available cosmetic products.
  • To optimize the balance between diagnostic accuracy and testing efficiency.

Main Methods:

  • Utilized the European Surveillance System on Contact Allergies list for initial allergen selection.
  • Conducted a 10-year PubMed literature review on cosmetic allergen reaction frequencies.
  • Cross-referenced potential allergens with international databases of retail cosmetic products.
  • Applied a 0.3% threshold for positive patch test reactions to determine inclusion.

Main Results:

  • Identified key allergens frequently causing positive patch test reactions in cosmetic dermatitis.
  • Verified the presence of selected allergens in commercially available cosmetic products.
  • Excluded allergens from baseline series, fragrances, and hair-specific products.

Conclusions:

  • A revised cosmetic series of 20 elements is proposed for improved diagnosis.
  • The updated series balances the identification of relevant allergens with practical testing constraints.
  • This reformulation aims to enhance the management of cosmetic contact dermatitis.