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Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Mechanisms and Management of Knee Anterior Cruciate Ligament Injury; A Review
Seyyed Mohsen Hosseininejad1,2, Mohammad Kazem Emami Meybodi2, Mehdi Raei3,4
1School of Medicine, Orthopedic Department, Golestan University of Medical Sciences, Gorgan, Iran.
Objectives:
This study aimed to clarify the debate on anterior cruciate ligament (ACL) injury management and the selection of patients for surgical or nonsurgical treatment.
Methods:
A retrospective, citation-based approach was employed to search for English literature that assessed management options and mechanisms for ACL injuries.
Results:
A variety of mechanical and neurocognitive mechanisms are involved in ACL injuries that could be used to develop practical prevention strategies. More precise preoperative clinical, and paraclinical assessments, as well as clarification of available treatment options for patients, would lead to individualized decisions on injury management, and thus to objective and subjective satisfaction. Prioritization of attentive physical therapy rehabilitation plans will also improve treatment outcomes.
Conclusion:
A better understanding of the ACL injury/patient characteristics will help to achieve optimal treatment outcomes for each individual and develop targeted and practical prevention strategies.
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