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Pulsed Field Ablation for Atrial Fibrillation in Fontan Palliation
Fouad Khalil1, Abhishek J Deshmukh2, Shane T Tsai1
1Department of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Journal of Cardiovascular Electrophysiology
|July 9, 2025
Summary
Pulsed-field ablation (PFA) offers a new treatment for atrial fibrillation (AF) in Fontan patients. This case study shows PFA is a feasible and successful option for AF ablation in this complex population.
Area of Science:
- Electrophysiology
- Interventional Cardiology
- Congenital Heart Disease
Background:
- Pulsed-field ablation (PFA) is an emerging therapy for atrial fibrillation (AF).
- Previous studies suggest PFA efficacy in congenital heart disease patients.
- PFA has not been previously reported in Fontan patients.
Observation:
- A 35-year-old patient with a history of Fontan palliation for hypoplastic left heart syndrome presented with AF.
- The patient underwent successful AF ablation using PFA.
- Procedure characteristics and potential benefits were documented.
Findings:
- Pulsed-field ablation (PFA) was successfully utilized for atrial fibrillation (AF) in a patient with a Fontan circulation.
- The ablation procedure demonstrated feasibility and immediate success.
Implications:
- This case suggests PFA may be a viable treatment option for AF in Fontan patients.
- Further research is needed to establish long-term outcomes and safety profiles of PFA in this unique population.
