Infrared spectroscopic analysis of urinary stone composition

To assess the composition of urinary stones in Lanzhou area and provide a reference basis for its clinical prevention and treatment.

A total of 1284 patients with urinary stones were included in the study. The differences in the distribution of stone components among different genders and ages were then analyzed.

The overall male-to-female ratio of the cases was 3.2:1. The average age of the patients was 45.1 ± 14.0 years old. The ratio between upper and lower urinary tract stones was 7.13:1. Mixed stone composition accounted for the majority, 79.0% (1014/1284), with calcium oxalate monohydrate + calcium oxalate dihydrate + carbonate apatite being the most prevalent at 35% (449/1284), and calcium oxalate monohydrate stones being the most prevalent of the single components at 17.8% (228/1284). Apatite carbonate 62.2% (191/307) and magnesium ammonium phosphate hexahydrate 9.8% (30/307) were significantly higher in female patients compared to apatite carbonate 55.2% (539/977) and 2.8% (27/977) in male patients. Calcium oxalate was significantly more prevalent in patients aged 18-60 years than in patients <18 and ≥60 years. The proportion of patients over the age of 60 with urinary stones (10.4%) was significantly higher than patients in other age groups.

Urological stones in Lanzhou area are mainly of mixed type, calcium oxalate monohydrate + calcium oxalate dihydrate + carbonate apatite is the most; with the increase of patient's age, the proportion of uric acid stones increases; the distribution of urinary stone components has significant differences with different genders of patients and different age groups, which is of great significance for clinical prevention and treatment.