Trends and Developments in Vulvar Lichen Sclerosus Research
Fan-Rong He1, Yan-Rui Lin1, Yu-Hua Wen1
1Department of Obstetrics and Gynecology The Air Force Hospital of Southern Theater Command Guangzhou China.
Health Science Reports
|July 10, 2025
Summary
This bibliometric analysis of vulvar lichen sclerosus (VLS) research highlights topical corticosteroids as a primary treatment. Recent studies increasingly focus on long-term management and quality of life, with growing VLS research output.
Area of Science:
- Dermatology
- Bibliometrics
- Medical Research Analysis
Background:
- Vulvar lichen sclerosus (VLS) is a prevalent chronic skin condition.
- A comprehensive bibliometric analysis of VLS research was lacking.
- This study provides an updated overview of VLS research status and trends.
Purpose of the Study:
- To conduct a bibliometric analysis of VLS research.
- To identify research trends and key characteristics in the VLS literature.
- To offer clinicians and researchers an overview of the current VLS research landscape.
Main Methods:
- Utilized Web of Science Core Collection (1994-2023).
- Analyzed 1698 publications using bibliometric tools (CiteSpace, VOSviewer, Pajek).
- Examined citation bursts and co-citation patterns.
Main Results:
- Topical corticosteroids are confirmed as the preferred primary treatment for VLS.
- Significant increase in VLS publications since 2018, led by the US and UK.
- Research focus shifted towards long-term management and quality of life, exploring mechanisms like immune regulation, oxidative stress, and genetics.
Conclusions:
- Increased institutional resource allocation for VLS prevention and long-term management is recommended.
- Further research into VLS pathogenesis and improved patient outcomes is warranted.


