An optical fiber caffeic acid sensor using a molecularly-imprinted chitosan membrane as a transducer

Caffeic acid is an antioxidant that demonstrates anti-inflammatory, anti-carcinogenic, and anti-bacterial properties. It adds health benefits and extends food product shelf-life. A low cost, field-applicable technique for quick detection of caffeic acid concentration in food products is attractive to the food industry. In this work, an optical fiber caffeic acid sensor was developed by integrating a molecularly imprinted polymer (MIP) with fiber optic spectrometry. An MIP membrane coated on the surface of an optical fiber selectively extracts and concentrates caffeic acid from a sample solution. The extracted caffeic acid was detected by transmitting a light beam through the fiber with caffeic acid's intrinsic optical absorption as the sensing signal. The use of MIP significantly enhanced the sensor's sensitivity and selectivity. The sensor achieved a detection limit of 5.2 ng/mL and could be used for rapid field detection or continuous monitoring of caffeic acid concentration in food production and processing lines.