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Guillain-Barré Syndrome in Chile: Incidence and Mortality (2013-2019)
Juan Francisco Idiáquez1, Rodrigo Salinas2,3, Gabriel Cea2,3
1Ellen and Martin Prosserman Centre for Neuromuscular Diseases, Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada, j.idiaquez@utoronto.ca.
Insights
The incidence of Guillain-Barré syndrome (GBS) in Chile is 1.46 per 100,000, with a 1.7% mortality rate. This rare autoimmune disorder shows a slight male predominance and a high survival rate of 98.3%.
Area of Science:
- Neurology
- Epidemiology
- Autoimmune Diseases
Background:
- Guillain-Barré syndrome (GBS) is a rare autoimmune disorder affecting the peripheral nervous system.
- Incidence rates of GBS vary globally, necessitating regional analyses.
Purpose of the Study:
- To analyze the incidence and mortality rates of Guillain-Barré syndrome (GBS) in Chile.
- To provide epidemiological data on GBS from 2013 to 2019.
Main Methods:
- Retrospective review of national hospital discharge records.
- Identification of GBS cases using ICD-10 code G61.0.
- Calculation of annual incidence and mortality rates, adjusted for population.
Main Results:
- 1,696 GBS cases identified between 2013 and 2019.
- Annual incidence rate of 1.46 per 100,000 population.
- Mortality rate of 1.7% and a survival rate of 98.3%, with a male predominance (58.8%).
Conclusions:
- GBS incidence in Chile aligns with global averages.
- The study highlights a high survival rate for GBS patients in Chile.
- Further research is recommended to investigate factors like rurality and climate influencing GBS.
Abstract:
Introduction: Guillain-Barré syndrome (GBS) is a rare autoimmune disorder of the peripheral nervous system with incidence rates varying across regions. Based on hospital discharge data, this study aimed to analyze the incidence and mortality of GBS in Chile between 2013 and 2019.
Methods:
A retrospective review of GBS cases, identified using the ICD-10 code G61.0, was conducted using national hospital discharge records. The incidence rates were calculated annually and adjusted for the population. Demographic and clinical variables, including sex, age, insurance type, and outcomes, were analyzed.
Results:
A total of 1,696 cases were identified, yielding an annual incidence rate of 1.46 per 100,000 (95% CI: 1.28-2.64). Most cases occurred in males (58.8%), with a mean age of 46.62 years. The mortality rate was 1.7%, and the high survival rate was 98.3%.
Conclusion:
The incidence of GBS in Chile is comparable to the global rates, with a slight male predominance and a high survival rate. Further studies are warranted to explore the potential rurality and climatic factors influencing GBS incidence in Chile.
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