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Published on: May 28, 2019
Acute Shock Liver in Inferior ST-Segment Elevation Myocardial infarct with Total Atrioventricular block: A Case
Mochamad Rizky Hendiperdana1, Sumardjo Sumardjo2
1Department of Cardiology Regional Public Hospital Pandan Arang of Boyolali, Indonesia. mhendiperdana@gmail.com.
Insights
Acute heart failure can cause liver dysfunction, known as shock liver, leading to high mortality. Prompt management of the underlying cause, like cardiogenic shock, can restore liver function and improve patient outcomes.
Area of Science:
- Cardiology
- Hepatology
- Critical Care Medicine
Background:
- Liver dysfunction is common in heart disease, particularly acute heart failure and cardiogenic shock.
- This condition, characterized by elevated liver enzymes, has high morbidity and mortality rates.
- Early recognition and prompt management are crucial for liver function recovery.
Purpose of the Study:
- To present a case of cardiogenic shock and acute liver dysfunction secondary to ST-elevation myocardial infarction (STEMI).
- To highlight the importance of addressing the underlying hemodynamic insult in managing shock liver.
- To demonstrate the potential for liver function recovery with appropriate treatment.
Main Methods:
- A 53-year-old male patient with inferior STEMI, cardiogenic shock, and complete atrioventricular block was treated.
- Management included inotropic and chronotropic support, post-MI anti-remodeling therapy, and anti-ischemic treatment.
- Hemodynamic stability was prioritized to improve systemic perfusion.
Main Results:
- The patient presented with STEMI, cardiogenic shock, complete AV block, acute shock liver, lactic acidosis, and acute renal failure.
- Following treatment aimed at improving hemodynamic status and addressing the underlying cardiac event, liver and renal functions normalized within a week post-discharge.
- Recovery of liver transaminases was observed after the elimination of the hemodynamic insult.
Conclusions:
- Shock liver management focuses on treating the underlying cause, primarily hemodynamic instability.
- Effective treatment of cardiogenic shock can lead to the recovery of liver function.
- This case underscores the link between cardiac events, hemodynamic compromise, and secondary liver dysfunction.
Abstract:
Liver dysfunction frequently accompanies heart diseases, especially in hemodynamically unstable acute heart failure or cardiogenic shock. This condition is marked by significant elevation of liver transaminases and brings high morbidity and mortality for > 50 % of cases. Despite the high mortality rate, early recognition with prompt management results in the recovery of liver function. A 53-year-old man presented with late-onset non-reperfused inferior STEMI. The patient presented with persistent chest pain and shortness of breath. The electrocardiogram showed atrioventricular (AV) block grade III and ST-segment elevation evolution in the inferior lead. The patient was diagnosed with a late-onset inferior STEMI with cardiogenic shock and total AV block complication, acute shock liver, lactic acidosis, and acute renal failure. We administered inotropic and chronotropic support drugs as well as post-MI anti-remodelling therapy to treat heart failure (HF) and left ventricular (LV) systolic dysfunction, such as angiotensin-converting enzyme inhibitor and aldosterone antagonist, after systemic perfusion improved. Anti-ischemic therapy, such as antithrombotics, was also administered. Renal and liver function test evaluation after a week of patient discharge showed normalization of these parameters. There is no definite treatment strategy for shock liver. The management strategy is directed at the treatment of underlying causes. Hemodynamic insult is the mainstay therapeutic target. Recovery of liver transaminases was demonstrated after the underlying insult had been eliminated.
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