Helical, Spring and Curled Nano/Micro Fibrous Structures for Tissue Engineering Application.

Area of Science:

• Materials Science
• Biotechnology
• Nanotechnology

Background:

• Helical, spring, curled, and hierarchically structured nano/microfibers have garnered significant interest.
• These structures possess unique characteristics and potential applications in tissue engineering and industry.
• Understanding fabrication parameters is crucial for their development.

Purpose of the Study:

• To review recent advancements in helical nano/microfiber research.
• To focus on processing techniques, structure, property characterization, and applications.
• To investigate mechanical and hydrodynamic parameters influencing helical fiber fabrication.

Main Methods:

• Coaxial electrospinning technique is highlighted.
• Use of polymers with varying elastic and conductive properties is crucial.
• Formation of helical structures is attributed to balanced electric and elastic forces in non-uniform electric fields.

Main Results:

• Helical structures form due to a balance between electric and elastic forces.
• Coaxial electrospinning is a key technique for producing these fibers.
• Properties include mechanical strength, high porosity, and biocompatibility.

Conclusions:

• Helical nanofibers show promise for tissue engineering scaffolds.
• Their ability to promote cellular activities is beneficial for regenerative medicine.
• These fibers are particularly suited for bone tissue engineering applications.