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Updated: Sep 16, 2025

Genome Editing in Astyanax mexicanus Using Transcription Activator-like Effector Nucleases TALENs
Published on: June 20, 2016
A genome assembly for Lahontan Cutthroat Trout, Oncorhynchus clarkii henshawi
Cheyenne Y Payne1,2, Merly Escalona3, Shannon R Kieran Blair4
1Institute of Marine Sciences, University of California, Santa Cruz, CA, United States.
Abstract:
Cutthroat trout (Oncorhynchus clarkii) are diverse Pacific salmonids widely distributed throughout western North America. Distinct lineages of cutthroat trout have been defined based on morphology, geography, and genetic differences. Several of these, including Lahontan cutthroat trout (Oncorhynchus clarkii henshawi), are classified as threatened or in danger of extinction. Despite their precarious conservation status, few genomic resources have been developed for these lineages. In an effort to promote the development and application of genomic approaches for research and conservation of this group, we present the first high-quality reference genome for Lahontan cutthroat trout. We use this genome assembly to describe genomic synteny and structural rearrangements with their sister species, rainbow trout (O. mykiss), as well as with the diverged westslope cutthroat trout (O. clarkii lewisi) lineage.

