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Related Concept Videos

The ABO Blood Group01:12

The ABO Blood Group

2.2K
The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
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Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
818
Blood Typing01:10

Blood Typing

1.5K
Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
1.5K
Blood Types02:20

Blood Types

18.4K
Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
18.4K
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

11.2K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
11.2K
Rh Blood Group01:19

Rh Blood Group

1.8K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.8K

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From educational to graded: redefining proficiency testing in ABO genotyping.

Human immunology·2026
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Transplant of serologic A1 but genotype A2 kidneys to ABO O and B recipients is feasible and safe.

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Evaluation of Chimerism Testing by Next-Generation Sequencing Using Insertion/Deletion Markers: Analytical Validation and Examples of Clinical Utilization.

The Journal of molecular diagnostics : JMD·2026
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Advancing ABO-histocompatibility: Impact of multiplexed ABO antibody immunoassay to increase precision in pediatric heart transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
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Underlying Diagnosis and RBC Transfusions Increase HLA Antibodies in Children before Hematopoietic Stem Cell Transplantation.

Transplantation and cellular therapy·2025
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Virtual crossmatching: Principles, practices, and the path forward-An American Society for Histocompatibility and Immunogenetics/College of American Pathologists collaborative.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2025

Related Experiment Video

Updated: Sep 16, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

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The case for mandating ABO genotyping to prevent catastrophic ABO-A subgroup errors

Cathi Murphey1, Matthias Kapturczak2

  • 1Southwest Immunodiagnostics, Inc, San Antonio, Texas, USA.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|July 11, 2025
PubMed
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No abstract available in PubMed .

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