Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

38
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
38
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

37
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
37
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

40
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
40
Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

46
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
46
Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

3.2K
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
3.2K
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

30
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
30

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Living Lab Concept in the Detection, Prevention and Monitoring of Geriatric Syndromes in Elderly Patients with Cardiovascular Disease-A Narrative Review.

Journal of clinical medicine·2026
Same author

An orthogeriatric quality improvement initiative from the European Academy for Medicine of Ageing (EAMA): enhancing osteoporosis treatment and fall prevention.

European geriatric medicine·2026
Same author

The Impact of Burnout on Body Composition in Medical Staff.

Medicina (Kaunas, Lithuania)·2026
Same author

Mapping the landscape of geriatric medicine education, training and practice in Europe.

Age and ageing·2026
Same author

Sarcopenia as a Multisystem Disorder-Connections with Neural and Cardiovascular Systems-A Related PRISMA Systematic Literature Review.

Life (Basel, Switzerland)·2026
Same author

Dopamine and the Gut Microbiota: Interactions Within the Microbiota-Gut-Brain Axis and Therapeutic Perspectives.

International journal of molecular sciences·2026

Related Experiment Video

Updated: Sep 16, 2025

Author Spotlight: Innovations in iTUG Test for Enhanced Risk Assessment and Cognitive Insights
05:26

Author Spotlight: Innovations in iTUG Test for Enhanced Risk Assessment and Cognitive Insights

Published on: October 25, 2024

1.2K

Cardiovascular Pharmacotherapy and Falls in Old People: Risks and Prevention-An Observational Case-Control Study.

Sorina Maria Aurelian1,2, Anca Iuliana Pîslaru3, Sabinne-Marie Albișteanu3

  • 1Clinic of Geriatrics, Hospital of Chronic Diseases "Sf. Luca", Faculty of Medicine, University of Medicine and Pharmacy "Carol Davila", 041915 Bucharest, Romania.

Journal of Clinical Medicine
|July 12, 2025
PubMed
Summary

Falls in older adults are linked to cardiovascular medications. Specific drugs like spironolactone, beta-blockers, and calcium channel blockers increase fall risk. Medication review and deprescribing can help prevent falls.

Keywords:
cardiovascular medicationfall riskolder adults

More Related Videos

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
07:21

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease

Published on: June 16, 2023

1.0K
Design and Analysis for Fall Detection System Simplification
08:05

Design and Analysis for Fall Detection System Simplification

Published on: April 6, 2020

10.8K

Related Experiment Videos

Last Updated: Sep 16, 2025

Author Spotlight: Innovations in iTUG Test for Enhanced Risk Assessment and Cognitive Insights
05:26

Author Spotlight: Innovations in iTUG Test for Enhanced Risk Assessment and Cognitive Insights

Published on: October 25, 2024

1.2K
Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
07:21

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease

Published on: June 16, 2023

1.0K
Design and Analysis for Fall Detection System Simplification
08:05

Design and Analysis for Fall Detection System Simplification

Published on: April 6, 2020

10.8K

Area of Science:

  • Geriatrics
  • Cardiology
  • Pharmacology

Background:

  • Falls are a leading cause of morbidity and mortality in older adults, often influenced by comorbidities and polypharmacy.
  • Cardiovascular diseases (CVDs) and their treatments are common in this population and may elevate fall risk.

Purpose of the Study:

  • To investigate the association between cardiovascular pharmacotherapy and fall risk in older adults.
  • To identify potential preventive strategies for falls in this demographic.

Main Methods:

  • An observational case-control study involving 200 participants over 55 years old.
  • Assessment using the Downton Fall Risk Index, comprehensive geriatric assessment, and analysis of CVD and medication use.

Main Results:

  • High fall risk group showed significant differences in systolic blood pressure, ankle brachial index, CVD prevalence, cholesterol, and triglyceride levels.
  • Spironolactone, beta-blockers, and calcium channel blockers were significantly associated with increased fall risk, particularly in combination.
  • Frailty, cognitive impairment, diabetes, and musculoskeletal conditions were additional risk factors.

Conclusions:

  • Cardiovascular diseases and their pharmacotherapy are significantly associated with increased fall risk in older adults.
  • Medication review, deprescribing, and individualized treatment plans are crucial for minimizing fall risk while managing CVD.