Related Experiment Videos
Switching monoamine oxidase inhibitors.
Drug Intelligence & Clinical Pharmacy
|November 1, 1985
Summary
Switching between monoamine oxidase inhibitors (MAOIs) typically requires a drug-free period. This case study suggests that direct substitution may be possible without adverse effects, challenging current guidelines for MAOI use.
Area of Science:
- Pharmacology
- Neuroscience
- Clinical Medicine
Background:
- Monoamine oxidase inhibitors (MAOIs) are critical antidepressants.
- Current guidelines recommend a drug-free interval when switching between MAOIs to prevent hypertensive crises.
- The evidence supporting this strict protocol is limited.