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Updated: Sep 16, 2025

Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation
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Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation

Published on: May 23, 2025

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Platelet-Induced NET in Liver Cirrhosis: Mitochondrial ROS-Mediated NETosis and Its Contribution to the

Xiaoming Wu1,2,3, Haijiao Jing1,2, Tao Jiang4

  • 1Department of Hematology, The First Hospital, Harbin Medical University, Harbin, China.

Liver International : Official Journal of the International Association for the Study of the Liver
|July 12, 2025
PubMed
Summary

Platelets in liver cirrhosis trigger neutrophil extracellular traps (NETs) via mitochondrial ROS and autophagy. This elevates clotting and impairs anticoagulant function, impacting the cirrhotic coagulation system.

Keywords:
autophagyliver cirrhosismitochondrial ROSneutrophil extracellular trapsplatelet

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