Hydroxyapatite-Coated Titanium Mesh: An Innovative Strategy for Guided Tissue Regeneration in Periodontal Therapy

Area of Science:

• Periodontal regeneration
• Biomaterials science
• Tissue engineering

Background:

• Guided tissue regeneration (GTR) is crucial for periodontal therapy.
• Titanium mesh offers biocompatibility and mechanical stability for regeneration.
• Hydroxyapatite (HA) coating may enhance titanium mesh osteoconductivity.

Purpose of the Study:

• To evaluate the efficacy of hydroxyapatite-coated titanium mesh in periodontal regeneration.
• To compare outcomes of coated versus uncoated titanium mesh in GTR procedures.
• To assess bone fill and clinical parameters in periodontal intrabony defects.

Main Methods:

• 40 patients with periodontal intrabony defects were randomized into two groups.
• Group A received HA-coated titanium mesh; Group B received uncoated titanium mesh.
• Cone-beam computed tomography (CBCT) and clinical parameters (PD, CAL) were assessed at baseline and 6 months.

Main Results:

• HA-coated mesh group showed significant PD reduction and CAL gain (P < 0.001).
• Bone fill percentage was significantly higher in the HA-coated group (72.3%) vs. uncoated group (54.6%, P < 0.05).
• No significant complications were reported in either group.

Conclusions:

• Hydroxyapatite-coated titanium mesh demonstrates superior periodontal regeneration outcomes.
• Enhanced osteoconductivity of HA contributes to improved bone and soft tissue healing.
• Coated mesh is a promising material for GTR in periodontal defects.