Cardiovascular Care Disruptions Among U.S. Adults During the COVID-19 Pandemic: Medication Use, Mortality, and

Efeturi M Okorigba1, Chekwube M Obianyo2, Said R Tindwa3

  • 1Internal Medicine, West Virginia University, Morgantown, USA.

Cureus
|July 14, 2025
PubMed

Insights

Cardiovascular disease (CVD) medication use saw slight declines during COVID-19, while CVD mortality significantly increased. Heart failure hospitalizations initially dropped but then recovered, highlighting the need for resilient healthcare systems.

Area of Science:

  • Public Health
  • Epidemiology
  • Cardiology

Background:

  • Cardiovascular diseases (CVDs) are a leading cause of death in the U.S., disproportionately impacting older adults and minorities.
  • Analysis of national patterns in CVD medication use, mortality, and hospitalization from 2019 to 2021 is crucial.

Purpose of the Study:

  • To examine trends in antihypertensive and lipid-lowering medication use.
  • To assess changes in CVD-related mortality (stroke, coronary heart disease, total heart disease).
  • To evaluate heart failure hospitalization rates before and during the COVID-19 pandemic.

Main Methods:

  • Retrospective analysis of Behavioral Risk Factor Surveillance System (BRFSS) data (2019-2021).
  • Stratification of medication use by sex, age, and race/ethnicity.
  • Statistical analysis including descriptive statistics, paired t-tests, and ANOVA.

Main Results:

  • Antihypertensive and cholesterol-lowering medication use remained stable overall but declined in some subgroups.
  • Adults with high blood pressure showed increased antihypertensive medication use (57.7% to 60.4%).
  • CVD mortality rates consistently increased from 2019 to 2021, with over 695,000 deaths in 2021.

Conclusions:

  • The COVID-19 pandemic correlated with reduced CVD medication adherence and increased cardiovascular mortality.
  • Heart failure hospitalizations initially decreased but showed partial recovery by 2021.
  • Findings emphasize the need for robust healthcare systems to manage chronic cardiovascular care disruptions.

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