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Cardiovascular Care Disruptions Among U.S. Adults During the COVID-19 Pandemic: Medication Use, Mortality, and
Efeturi M Okorigba1, Chekwube M Obianyo2, Said R Tindwa3
1Internal Medicine, West Virginia University, Morgantown, USA.
Insights
Cardiovascular disease (CVD) medication use saw slight declines during COVID-19, while CVD mortality significantly increased. Heart failure hospitalizations initially dropped but then recovered, highlighting the need for resilient healthcare systems.
Area of Science:
- Public Health
- Epidemiology
- Cardiology
Background:
- Cardiovascular diseases (CVDs) are a leading cause of death in the U.S., disproportionately impacting older adults and minorities.
- Analysis of national patterns in CVD medication use, mortality, and hospitalization from 2019 to 2021 is crucial.
Purpose of the Study:
- To examine trends in antihypertensive and lipid-lowering medication use.
- To assess changes in CVD-related mortality (stroke, coronary heart disease, total heart disease).
- To evaluate heart failure hospitalization rates before and during the COVID-19 pandemic.
Main Methods:
- Retrospective analysis of Behavioral Risk Factor Surveillance System (BRFSS) data (2019-2021).
- Stratification of medication use by sex, age, and race/ethnicity.
- Statistical analysis including descriptive statistics, paired t-tests, and ANOVA.
Main Results:
- Antihypertensive and cholesterol-lowering medication use remained stable overall but declined in some subgroups.
- Adults with high blood pressure showed increased antihypertensive medication use (57.7% to 60.4%).
- CVD mortality rates consistently increased from 2019 to 2021, with over 695,000 deaths in 2021.
Conclusions:
- The COVID-19 pandemic correlated with reduced CVD medication adherence and increased cardiovascular mortality.
- Heart failure hospitalizations initially decreased but showed partial recovery by 2021.
- Findings emphasize the need for robust healthcare systems to manage chronic cardiovascular care disruptions.
Abstract:
Background Cardiovascular diseases (CVDs) are the leading cause of death in the United States, with mortality disproportionately affecting older adults and racial/ethnic minorities. This study analyzes national patterns in CVD medication use, mortality, and hospitalization from 2019 to 2021. Objectives To examine patterns of antihypertensive and lipid-lowering medication use, trends in CVD-related mortality (stroke, coronary heart disease, and total heart disease), and hospitalization rates for heart failure among the U.S. population before and during the COVID-19 pandemic. Methods This retrospective study utilized Behavioral Risk Factor Surveillance System (BRFSS) data from 2019 to 2021, a nationally representative telephone survey coordinated by the CDC. Trends in cardiovascular medication use were stratified by sex, age, and race/ethnicity. Descriptive statistics, paired t-tests, and one-way ANOVA were used to assess temporal changes. A p-value <0.05 indicates statistical significance. Analyses were conducted using SPSS version 30 (IBM Corp., Armonk, USA). Results The use of antihypertensive and cholesterol-lowering medications remained stable overall but declined slightly in some subgroups during 2020. Among adults with high blood pressure, antihypertensive medication use increased from 57.7% (95% CI: 57.1-58.4) in 2019 to 60.4% (95% CI: 59.6-61.1) in 2021. Similarly, cholesterol-lowering medication use rose from 28.9% (95% CI: 28.6-29.2) to 31.0% (95% CI: 30.6-31.3). Heart failure hospitalizations among Medicare beneficiaries aged ≥65 years declined from 27.72 per 1,000 (95% CI: 27.66-27.78) in 2019 to 22.87 (95% CI: 22.81-22.92) in 2020, before increasing to 25.91 (95% CI: 25.85-25.97) in 2021. Cerebrovascular, coronary heart disease, and overall heart disease mortality rates consistently increased from 2019 to 2021, with heart disease deaths rising from 161.5 to 173.8 per 100,000, totaling over 695,000 deaths in 2021. Conclusions The COVID-19 pandemic was associated with modest declines in CVD medication use and significant increases in cardiovascular mortality, particularly among high-risk populations. Hospitalizations for heart failure initially decreased but partially recovered by 2021. These findings underscore the necessity for resilient healthcare systems and targeted strategies to mitigate pandemic-related disruptions in chronic cardiovascular care.
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