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An Adaptive Generative 3D VNet Model for Enhanced Monkeypox Lesion Classification Using Deep Learning and Augmented

Shivani Joshi1, Rajiv Kumar2, Avinash Dwivedi2

  • 1School of Computer Science & Engineering, Galgotias University, Greater Noida, India. shivani1275@gmail.com.

Journal of Imaging Informatics in Medicine
|July 14, 2025
PubMed
Summary

A novel Adaptive Generative 3D VNet model effectively detects monkeypox lesions using augmented data. This deep learning approach significantly improves classification accuracy, crucial for timely diagnosis and treatment planning.

Keywords:
Adaptive fusionAugmented imagesFlippingFusion layerHausdorff distanceJaccard IndexMonkeypox lesionsTraditional 2D models

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Dermatology

Background:

  • Monkeypox incidence is rising, necessitating accurate diagnostic tools for effective treatment.
  • Limited labeled data presents a significant challenge for developing robust disease detection models.

Purpose of the Study:

  • To design and evaluate an effective monkeypox detection and classification model using deep learning.
  • To address the challenge of limited labeled data by generating synthetic augmented images.

Main Methods:

  • A novel Adaptive Generative 3D VNet model integrating data augmentation, deep learning, and adaptive fusion.
  • Utilizing an Adaptive Generative Network for data augmentation (cropping, rotation, flipping) to increase dataset diversity.
  • Employing a 3D VNet for volumetric image processing to capture spatial lesion relationships and an adaptive fusion layer for combining predictions.

Main Results:

  • The Adaptive Generative 3D VNet model demonstrated superior performance compared to traditional 2D models.
  • Achieved high classification accuracy (98.8%) and precision (98.5%) on the Monkeypox Skin Lesion Dataset.
  • Significantly improved classification robustness, particularly with limited labeled data.

Conclusions:

  • The proposed Adaptive Generative 3D VNet model offers a robust and accurate solution for monkeypox lesion classification.
  • Effective mitigation of limited data challenges through synthetic data generation and adaptive fusion.
  • The model shows promise for enhancing diagnostic capabilities in clinical settings for monkeypox.