Complementing interpretable machine learning with synergistic analytical strategies for thyroid cancer recurrence
Souichi Oka1, Yoshiyasu Takefuji2
1Science Park Corporation, 3-24-9 Iriya-Nishi Zama-shi, Kanagawa 252-0029, Japan.
High predictive accuracy in thyroid cancer recurrence models does not guarantee reliable feature importance. Integrative approaches combining machine learning with statistical methods are crucial for robust risk factor identification.
Area of Science:
- Oncology
- Biostatistics
- Artificial Intelligence
Background:
- Interpretable machine learning models are increasingly used for disease prediction.
- XGBoost and SHAP are popular for their predictive accuracy and explainability.
- Concerns exist regarding the reliability of feature importance derived from these models.
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