Related Experiment Video
Updated: Apr 10, 2026

Transplantation of Olfactory Ensheathing Cells to Evaluate Functional Recovery after Peripheral Nerve Injury
Published on: February 23, 2014
Microsurgical reconstruction of lingual nerve in 130 patients without nerve grafting
Federico Biglioli1, Elisabetta De Simone1, Alessandro Lozza2
1Maxillo-Facial Surgery Department, San Paolo Hospital, University of Milan, Milan, Italy.
Abstract:
Lingual Nerve Injury (LNI) typically results in loss of sensation and pain, which can significantly impact social life and cause personal discomfort. Microsurgical reconstruction of the lingual nerve (LN) has been shown to alleviate these symptoms, leading to satisfactory functional recovery. Between January 2009 and December 2023, 149 patients underwent direct microneurorrhaphy of the LN, with 130 patients meeting our inclusion criteria. All patients were evaluated preoperatively and one year postoperatively using clinical and neurophysiological assessments (Trigeminal Sensitivity Test) to evaluate Residual Tactile Capacity (RTC), Residual Pain Capacity (RPC), and Masseteric Inhibitory Reflex (MIR). Additionally, all patients completed a postoperative questionnaire twelve months after surgery to assess quality of life. The analysis showed an increase in RTC in 115 patients, a decrease in 5 cases, and no change in 10 cases. RPC improved in 115 patients, decreased in 2 cases, and remained unchanged in 13 cases. Complete recovery of MIR was observed in 17 patients. In the remaining cases, increased latencies of Sp1 and Sp2 were recorded, but these changes were consistent with functional recovery.
More Related Videos
19:53Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
06:48Ethanol-Induced Cervical Sympathetic Ganglion Block Applications for Promoting Canine Inferior Alveolar Nerve Regeneration Using an Artificial Nerve
Published on: November 30, 2018