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I2-Mediated One-Pot Three-Component Tandem Cyclization: Synthesis of 1H-Pyrrolo[3,4-c]quinoline-1,3(2H)-diones and
Xueyan Lv1, Yuxuan Wang1, Ziqi Song1
1Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, People's Republic of China.
Abstract:
An I2-mediated one-pot three-component tandem cyclization for the synthesis of 1H-pyrrolo[3,4-c]quinoline-1,3(2H)-diones (PQLs) has been reported. Starting from aromatic amines and maleimides, when aromatic aldehydes or di-tert-butyl peroxide (DTBP) were present, different substitution types of PQLs were obtained. It was noted that DTBP could be used as the C4 unit for constructing the heterocyclic skeleton under the current conditions. Favorable photophysical properties of PQLs have made them candidate compounds for a new generation of innovative fluorescent probes.
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