Comprehensive Review of Endometriosis Care
Erin T Carey1, Jacqueline M K Wong, Zaraq Khan
1Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; the Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, Oregon; and the Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota.
Obstetrics and Gynecology
|July 17, 2025
Summary
Endometriosis, a chronic inflammatory disorder affecting 10% of reproductive-aged individuals, causes pelvic pain and subfertility. Research highlights its systemic nature and need for diverse, personalized management strategies.
Area of Science:
- Reproductive Medicine
- Gynecology
- Chronic Inflammatory Disorders
Background:
- Endometriosis affects 10% of reproductive-aged individuals, causing pain, dysmenorrhea, and subfertility.
- It is an estrogen-dependent disorder with identified genetic and environmental risk factors.
- Emerging research indicates endometriosis is a systemic disease impacting nonreproductive systems.
Purpose of the Study:
- To review current understanding of endometriosis, including its phenotypes, diagnosis, and management.
- To highlight the need for interdisciplinary, patient-centered approaches.
- To emphasize the importance of addressing treatment disparities through diverse cohort analysis.
Main Methods:
- Review of existing literature on endometriosis.
- Analysis of diagnostic modalities including clinical evaluation, imaging (ultrasonography, MRI), and surgical staging.
- Discussion of current medical (hormonal modulation) and surgical treatment strategies.
Main Results:
- Endometriosis presents with diverse phenotypes (superficial peritoneal, ovarian endometriomas, deep endometriosis) with unclear interrelationships.
- Advanced imaging enhances diagnostic accuracy.
- Medical and surgical interventions are key for symptom management and refractory cases.
Conclusions:
- Comprehensive, interdisciplinary management incorporating novel diagnostics and therapies is crucial.
- Patient-centered care models and addressing treatment access disparities are essential.
- Research on diverse populations is needed for personalized and effective endometriosis strategies.
Related Concept Videos
01:29Chronic Pancreatitis II: Collaborative Care
130
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
130
01:28Infertility in Females
406
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
406
01:18Endocarditis III: Medical Management
20
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
20
01:21Inflammatory Bowel Disease V: Surgical Management
221
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
221
01:28Urologic Endoscopic Procedure: Cystoscopic Examination
374
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
374
01:25Urinary Tract Calculi VI: Surgical Management
35
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
35